Histotripsy

Histotripsy is a form of targeted ultrasound that precisely delivers pulsed sound waves to tumors, creating expanding and collapsing bubbles to destroy the tumors while sparing surrounding tissue. This minimally invasive procedure, approved to treat liver cancer, does not require incisions or any penetration of the skin, nor does it involve radiation. The mechanical forces created by the pulsing sound waves break down tumors at the cellular level, liquifying them to be eliminated through the body’s lymphatic system.

During the procedure, performed under general anesthesia and guided by ultrasound imaging at Memorial Hermann-Texas Medical Center, the head of the ultrasound device rests on the area of the abdomen where the tumors can be targeted by the sound waves. As the highly amplified sound waves rapidly pulse, bubble clouds from gases within the tissue form and move over the tumor, breaking down and destroying tumor cells. The targeting of the tumor means the surrounding healthy tissue can be preserved.

With visualization provided by the imaging ultrasound, the doctor can see when the tumor has been eliminated and target any other tumors during the treatment session. The procedure time varies based on the number of tumors and their location, but several tumors can be treated in one session, minimizing the need for multiple treatments.

While patients may experience some discomfort or pain immediately after the procedure, the minimally invasive approach means the risk of infection, bleeding and complications is minimized. Many patients return home the same day as the procedure and resume their normal activities with few restrictions.

Clinical trials indicate that histotripsy safely and effectively destroys tumor tissue without the need for radiation or other heat-generating treatments. While it is fully approved by the FDA for treatment of primary and metastatic liver tumors, it’s important to note that several factors impact whether it may be an effective treatment for some individuals. A doctor will discuss the benefits and risks of histotripsy with each patient.

Why Memorial Hermann?

Memorial Hermann Cancer Center – Texas Medical Center has acquired a histotripsy system for treatment of liver cancer. Affiliated physicians with experience treating liver cancer using other approved technology have also been trained to use histotripsy and have successfully completed treatment procedures at Memorial Hermann Cancer Center – Texas Medical Center. Collectively, they have partnered with Memorial Hermann to bring this novel technology, which is limited in many places, to Greater Houston. Patients now have more options when it comes to treating their liver cancer.